Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2,2-Dimethyl-4-[4-(pyridin-3-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide
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 PubChem ID
CID: 44330198
Canonical SMILES
CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2cccnc2)cc1
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Compound Formula C18H21N3O5S2
Compound Structure
Protein Name
 Protein Info 
Disintegrin and metalloproteinase domain-containing protein 17
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAM clan
>
Metallo protease M12B subfamily
Uniprot ID
P78536
Gene Name
ADAM17
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.9 nM