Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(7S,8R,11S)-11-Benzoyl-8-{3-[3-methoxy-5-(2-methoxy-ethoxy)-phenyl]-propyl}-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7-carboxylic acid hydroxyamide
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 PubChem ID
CID: 44330197
Canonical SMILES
COCCOc1cc(CCC[C@@H]2[C@H](CCCCOc3ccc(C[C@H](NC2=O)C(=O)c2ccccc2)cc3)C(=O)NO)cc(OC)c1
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Compound Formula C36H44N2O8
Compound Structure
Protein Name
 Protein Info 
Disintegrin and metalloproteinase domain-containing protein 17
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAM clan
>
Metallo protease M12B subfamily
Uniprot ID
P78536
Gene Name
ADAM17
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 74 nM