Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine
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 PubChem ID
CID: 62065
SID: 15071198
Canonical SMILES
COc1cc(CC(C)N)c(OC)cc1Br
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Compound Formula C11H16BrNO2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P14842
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000238 A7r5
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
EC50 = 60 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  4
1
EC50 = 22 nM
   TI
   LI
   LO
   TS
2
EC50 = 72 nM
   TI
   LI
   LO
   TS
3
Ki = 13 nM
   TI
   LI
   LO
   TS
4
Ki = 32 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 72 nM
2 Ki = 0.1 nM
3 Ki = 2.2 nM
4 Ki = 22 nM
5 Ki = 32 nM
6 Ki = 41 nM