Brief Information of the Compound and Protein
Compound Name
7-(3,5-Bis-trifluoromethyl-benzyl)-5-p-tolyl-7,8,9,10-tetrahydro-1,7,10a-triaza-cyclohepta[b]naphthalene-6,11-dione
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PubChem ID
CID: 10816374
SID: 15856480
Canonical SMILES
Cc1ccc(cc1)-c1c2C(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)CCCn2c(=O)c2ncccc12
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Compound Formula C28H21F6N3O2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 0.85 nM
   TI
   LI
   LO
   TS