Brief Information of the Compound and Protein
Compound Name
(3,4-dichlorophenyl)-[4-(fluoromethyl)-4-[[(6-pyrazol-1-ylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
    Show/Hide
PubChem ID
CID: 10576554
SID: 15604706
Canonical SMILES
FCC1(CNCc2cccc(n2)-n2cccn2)CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1
    Show/Hide
Compound Formula C23H24Cl2FN5O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000803 HA7 Homo sapiens (Human)  1
1
EC50 = 309.03 nM
   TI
   LI
   LO
   TS