Brief Information of the Compound and Protein
Compound Name
4-fluoro-7-[2-hydroxy-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-3,4'-(hexahydropyridine)]-1-ylpropoxy]-1-indanone
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PubChem ID
CID: 15548722
Canonical SMILES
OC(COc1ccc(F)c2CCC(=O)c12)CN1CCC2(CC1)OCc1c2ccc2ccccc12
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Compound Formula C28H28FNO4
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 3.5 nM
   TI
   LI
   LO
   TS
2
Ki = 2.3 nM
   TI
   LI
   LO
   TS