Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine
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 PubChem ID
CID: 5401
SID: 14805011
Canonical SMILES
COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1
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Compound Formula C19H25N5O4
Compound Structure
Protein Name
 Protein Info 
Alpha-1D adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Adrenergic receptor
Uniprot ID
P25100
Gene Name
ADRA1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.85 nM
2 Ki = 2 nM
3 Ki = 3.467 nM
4 Ki = 3.5 nM
5 Ki = 3.7 nM
6 Ki = 3.981 nM