Brief Information of the Compound and Protein
Compound Name
(2-Chloro-benzyl)-[(2S,3S)-2-(3-chloro-phenyl)-1-aza-bicyclo[2.2.2]oct-3-yl]-amine
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PubChem ID
CID: 44346524
Canonical SMILES
Clc1cccc(c1)[C@H]1[C@@H](NCc2ccccc2Cl)C2CCN1CC2
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Compound Formula C20H22Cl2N2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  2
1
IC50 = 229.09 nM
   TI
   LI
   LO
   TS
2
IC50 = 230 nM
   TI
   LI
   LO
   TS