Brief Information of the Compound and Protein
Compound Name
1,4,5,6-Tetrahydro-pyrimidine-5-carboxylic acid but-2-ynyl ester hydrochloride
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PubChem ID
CID: 45259463
Canonical SMILES
CC#CCOC(=O)C1CN=CNC1.Cl
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Compound Formula C9H13ClN2O2
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P12657
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9 Mus musculus (Mouse)  3
1
EC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 9.01 nM
   TI
   LI
   LO
   TS
3
Ki = 14 nM
   TI
   LI
   LO
   TS