Brief Information of the Compound and Protein
Compound Name
1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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PubChem ID
CID: 1400
SID: 14873050
Canonical SMILES
Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)C
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Compound Formula C16H19N5
Compound Structure
Protein Name
Tyrosine-protein kinase Lck
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Src family
Uniprot ID
P06239
Gene Name
LCK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 151 nM
2 IC50 = 250 nM
3 Ki = 63.1 nM