Brief Information of the Compound and Protein
Compound Name
1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[3,4-d]pyrimidine
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PubChem ID
CID: 4878
SID: 14898464
Canonical SMILES
CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(N)ncnc12
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Compound Formula C15H16ClN5
Compound Structure
Protein Name
Tyrosine-protein kinase Lck
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Src family
Uniprot ID
P06239
Gene Name
LCK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM
2 Ki = 0.7943 nM