Brief Information of the Compound and Protein
Compound Name
N-[(2R)-1-[acetyl-[(2-methoxyphenyl)methyl]amino]-3-(1H-indol-3-yl)propan-2-yl]-2-(4-piperidin-1-ylpiperidin-1-yl)acetamide
    Show/Hide
PubChem ID
CID: 3086681
SID: 14764005
Canonical SMILES
COc1ccccc1CN(C[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CN1CCC(CC1)N1CCCCC1)C(C)=O
    Show/Hide
Compound Formula C33H45N5O3
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  2
1
IC50 = 0.15 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.23 nM
   TI
   LI
   LO
   TS