Brief Information of the Compound and Protein
Compound Name
(E)-3-(3-Bromo-4-hydroxy-5-methoxy-phenyl)-N-{4-[(E)-3-(3-bromo-4-hydroxy-5-methoxy-phenyl)-2-cyano-acryloylamino]-butyl}-2-cyano-acrylamide
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PubChem ID
CID: 11802348
SID: 16915805
Canonical SMILES
COc1cc(/C=C(\C#N)C(=O)NCCCCNC(=O)/C(C#N)=C/c2cc(Br)c(O)c(OC)c2)cc(Br)c1O
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Compound Formula C26H24Br2N4O6
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000185 HER14 Mus musculus (Mouse)  1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS