Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydroxyphenyl)prop-2-enamido]butyl}-3-(3,4,5-trihydroxyphenyl)prop-2-enamide
    Show/Hide
 PubChem ID
CID: 5329258
SID: 14961231
Canonical SMILES
Oc1cc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O
    Show/Hide
Compound Formula C24H22N4O8
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000185 HER14
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 600 nM
2 IC50 = 21000 nM