Brief Information of the Compound and Protein
Compound Name
(2E)-3-(3-bromo-4,5-dihydroxyphenyl)-2-{[(1E)-2-(3-bromo-4,5-dihydroxyphenyl)-1-cyanoeth-1-ene-1-]sulfonyl}prop-2-enenitrile
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PubChem ID
CID: 5329271
SID: 15706816
Canonical SMILES
Oc1cc(\C=C(/C#N)S(=O)(=O)C(=C\c2cc(O)c(O)c(Br)c2)\C#N)cc(Br)c1O
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Compound Formula C18H10Br2N2O6S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000185 HER14 Mus musculus (Mouse)  1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 850 nM
2 IC50 = 1400 nM