Brief Information of the Compound and Protein
Compound Name
(2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]butyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide
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PubChem ID
CID: 5329257
SID: 14907095
Canonical SMILES
Oc1ccc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O
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Compound Formula C24H22N4O6
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000185 HER14 Mus musculus (Mouse)  1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 600 nM
2 IC50 = 4300 nM