Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3-trifluoromethyl-1H-pyrazole
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 PubChem ID
CID: 115239
SID: 14853753
Canonical SMILES
CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(F)cc1)C(F)(F)F
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Compound Formula C17H12F4N2O2S
Compound Structure
Protein Name
 Protein Info 
Prostaglandin G/H synthase 2
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35354
Gene Name
PTGS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000880 COS
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 66 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 50 nM
2 IC50 = 90 nM
3 IC50 = 100 nM
4 IC50 = 310 nM
5 IC50 = 1100 nM