Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide
    Show/Hide
 PubChem ID
CID: 5358
SID: 14825017
Canonical SMILES
CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
    Show/Hide
Compound Formula C14H21N3O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 341 nM
   TI
   LI
   LO
   TS
2
Ki = 440 nM
   TI
   LI
   LO
   TS
CL000803 HA7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 398.11 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 398.11 nM
2 Ki = 230 nM
3 Ki = 330 nM
4 Ki = 407.1 nM
5 Ki = 440 nM