Brief Information of the Compound and Protein
Compound Name
5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,7]naphthyridine-6-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
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PubChem ID
CID: 10414428
SID: 15432131
Canonical SMILES
Cn1c(C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(-c2ccc(F)cc2)c2cccnc2c1=O
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Compound Formula C25H16F7N3O2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 1.1 nM
   TI
   LI
   LO
   TS