Brief Information of the Compound and Protein
Compound Name
1-(2-Chloro-benzyl)-3-[4-(4-fluoro-phenyl)-2-methyl-1-oxo-1,2-dihydro-isoquinolin-3-yl]-1-methyl-urea
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PubChem ID
CID: 10253192
SID: 15256534
Canonical SMILES
CN(Cc1ccccc1Cl)C(=O)Nc1c(-c2ccc(F)cc2)c2ccccc2c(=O)n1C
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Compound Formula C25H21ClFN3O2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 480 nM
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