Brief Information of the Compound and Protein
Compound Name
3-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-methyl-4-phenyl-2H-isoquinolin-1-one
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PubChem ID
CID: 10005824
SID: 14985690
Canonical SMILES
Cn1c(COCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(-c2ccccc2)c2ccccc2c1=O
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Compound Formula C26H19F6NO2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS