Brief Information of the Compound and Protein
Compound Name
3-[(2-Methoxy-benzylamino)-methyl]-2-methyl-4-phenyl-2H-isoquinolin-1-one
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PubChem ID
CID: 10317867
SID: 15327139
Canonical SMILES
COc1ccccc1CNCc1c(-c2ccccc2)c2ccccc2c(=O)n1C
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Compound Formula C25H24N2O2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS