Brief Information of the Compound and Protein
Compound Name
7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyridine-6-carboxylic acid (3,5-dimethyl-benzyl)-methyl-amide
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PubChem ID
CID: 10071073
SID: 15056446
Canonical SMILES
CN(Cc1cc(C)cc(C)c1)C(=O)c1c(-c2ccc(C)cc2)c2cccnc2c(=O)n1C
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Compound Formula C27H27N3O2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  1
1
IC50 = 4.4 nM
   TI
   LI
   LO
   TS