Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-ethyl-6-methylpyridin-2(1H)-one
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 PubChem ID
CID: 65002
SID: 12014636
Canonical SMILES
CCc1cc(NCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C
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Compound Formula C16H15Cl2N3O2
Compound Structure
Protein Name
 Protein Info 
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM
2 IC50 = 19 nM
3 IC50 = 20 nM
4 IC50 = 35 nM
5 IC50 = 100 nM
6 IC50 = 110 nM
7 IC50 = 130 nM
8 IC50 = 150 nM
9 IC50 = 220 nM
10 IC50 = 230 nM
11 IC50 = 270 nM
12 IC50 = 280 nM
13 IC50 = 290 nM
14 IC50 = 320 nM
15 IC50 = 430 nM
16 IC50 = 800 nM
17 IC50 = 850 nM
18 IC50 = 1405 nM
19 IC50 = 1600 nM
20 IC50 = 2700 nM
21 IC50 = 7700 nM
22 IC50 = 15000 nM
23 IC50 > 10000 nM
24 IC50 > 60000 nM