Brief Information of the Compound and Protein
Compound Name
3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-phenyl)-2-(3,4-dihydroxy-benzoyl)-acrylonitrile
    Show/Hide
PubChem ID
CID: 44345182
Canonical SMILES
COc1cc(\C=C(/C#N)C(=O)c2ccc(O)c(O)c2)cc(CSCc2ccccc2)c1O
    Show/Hide
Compound Formula C25H21NO5S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 750 nM
2 IC50 = 4500 nM