Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-Hydroxy-3-methoxy-5-phenylsulfanylmethyl-benzylidene)-malononitrile
    Show/Hide
 PubChem ID
CID: 44345469
Canonical SMILES
COc1cc(C=C(C#N)C#N)cc(CSc2ccccc2)c1O
    Show/Hide
Compound Formula C18H14N2O2S
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 6000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6700 nM
2 IC50 = 6760.83 nM