Brief Information of the Compound and Protein
Compound Name
(E)-3-[3-(5-Chloro-benzothiazol-2-ylsulfanylmethyl)-4-hydroxy-5-methoxy-phenyl]-2-cyano-acrylamide
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PubChem ID
CID: 44345396
Canonical SMILES
COc1cc(\C=C(/C#N)C(N)=O)cc(CSc2nc3cc(Cl)ccc3s2)c1O
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Compound Formula C19H14ClN3O3S2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 4500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4400 nM
2 IC50 = 83176.38 nM
3 IC50 > 83000 nM