Brief Information of the Compound and Protein
Compound Name
(E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-p-tolylsulfanylmethyl-phenyl)-acrylamide
    Show/Hide
PubChem ID
CID: 44345648
Canonical SMILES
COc1cc(\C=C(/C#N)C(N)=O)cc(CSc2ccc(C)cc2)c1O
    Show/Hide
Compound Formula C19H18N2O3S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1737.8 nM
2 IC50 = 1750 nM
3 IC50 = 8700 nM