Brief Information of the Compound and Protein
Compound Name
(E)-3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-phenyl)-2-cyano-acrylamide
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PubChem ID
CID: 44345431
Canonical SMILES
COc1cc(\C=C(/C#N)C(N)=O)cc(CSCc2ccccc2)c1O
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Compound Formula C19H18N2O3S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 12500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 891.25 nM
2 IC50 = 900 nM
3 IC50 = 1950 nM