Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(20RS)-2-Amino-N-(4-ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-10-yl)-acetamide hydrochloride
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 PubChem ID
CID: 368335
Canonical SMILES
CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1.Cl
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Compound Formula C22H21ClN4O5
Compound Structure
Protein Name
 Protein Info 
DNA topoisomerase 1
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
P11387
Gene Name
TOP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 570 nM
   TI
   LI
   LO
   TS
2
IC50 > 30000 nM
   TI
   LI
   LO
   TS