Brief Information of the Compound and Protein
Compound Name
(20RS)-Amino-acetic acid 10-amino-4-ethyl-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-4-yl ester hydrochloride
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PubChem ID
CID: 45264950
Canonical SMILES
CCC1(OC(=O)CN)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(N)cccc3nc2-1.Cl
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Compound Formula C22H21ClN4O5
Compound Structure
Protein Name
DNA topoisomerase 1
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
P11387
Gene Name
TOP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  2
1
IC50 = 5500 nM
   TI
   LI
   LO
   TS
2
IC50 = 6800 nM
   TI
   LI
   LO
   TS