Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(20RS)-1N-(7-ethyl-7-hydroxy-8,11-dioxo-7,8,11,13-tetrahydro-10H-[1,3]dioxolo[5,4-g]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-15-yl)-2-aminoacetamide hydrochloride
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 PubChem ID
CID: 45264982
Canonical SMILES
CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)c4c(cc3nc2-1)OCO4.Cl
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Compound Formula C23H21ClN4O7
Compound Structure
Protein Name
 Protein Info 
DNA topoisomerase 1
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
P11387
Gene Name
TOP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
2
IC50 > 30000 nM
   TI
   LI
   LO
   TS