Brief Information of the Compound and Protein
Compound Name
(19S)-7-chloro-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
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PubChem ID
CID: 10156768
SID: 15149904
Canonical SMILES
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(Cl)cc4cc3Cn1c2=O
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Compound Formula C20H15ClN2O4
Compound Structure
Protein Name
DNA topoisomerase 1
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
P11387
Gene Name
TOP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
IC50 = 140 nM
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