Brief Information of the Compound and Protein
Compound Name
(20RS)-4-Hydroxy-4-(2-hydroxy-ethyl)-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione
    Show/Hide
PubChem ID
CID: 14440698
Canonical SMILES
OCCC1(O)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O
    Show/Hide
Compound Formula C20H16N2O5
Compound Structure
Protein Name
DNA topoisomerase 1
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
P11387
Gene Name
TOP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
IC50 = 9600 nM
   TI
   LI
   LO
   TS