Brief Information of the Compound and Protein
Compound Name
(20RS)-8-ethyl-8-hydroxy-2,3,8,9,12,14-hexahydro-11H-[1,4]dioxino[3,2-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-9,12-dione
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PubChem ID
CID: 44324446
Canonical SMILES
CCC1(O)C(=O)OCc2c1cc1-c3nc4cc5OCCOc5cc4cc3Cn1c2=O
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Compound Formula C22H18N2O6
Compound Structure
Protein Name
DNA topoisomerase 1
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
P11387
Gene Name
TOP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
IC50 = 470 nM
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