Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5S)-16-amino-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(24),2,4(9),13,15,17(21),22-heptaene-6,10-dione
    Show/Hide
 PubChem ID
CID: 468669
SID: 14781662
Canonical SMILES
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc5OCOc5c(N)c4cc3Cn1c2=O
    Show/Hide
Compound Formula C21H17N3O6
Compound Structure
Protein Name
 Protein Info 
DNA topoisomerase 1
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
P11387
Gene Name
TOP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS