Brief Information of the Compound and Protein
Compound Name
(19S)-19-ethyl-8,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
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PubChem ID
CID: 135403790
SID: 16293187
Canonical SMILES
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cccc(O)c4cc3Cn1c2=O
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Compound Formula C20H16N2O5
Compound Structure
Protein Name
DNA topoisomerase 1
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
P11387
Gene Name
TOP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
IC50 = 870 nM
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