Brief Information of the Compound and Protein
Compound Name
((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(4-methoxy-benzyl)-amine
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PubChem ID
CID: 44321519
Canonical SMILES
COc1ccc(CN[C@H]2C3CCN(CC3)[C@H]2C(c2ccccc2)c2ccccc2)cc1
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Compound Formula C28H32N2O
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000228 IM-9 Homo sapiens (Human)  2
1
IC50 = 343 nM
   TI
   LI
   LO
   TS
2
IC50 = 346.74 nM
   TI
   LI
   LO
   TS