Brief Information of the Compound and Protein
Compound Name
2-[[4-[[(2-amino-4-oxo-3H-pyrido[2,3-d]pyrimidin-6-yl)-methylamino]methyl]benzoyl]amino]pentanedioic acid
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PubChem ID
CID: 135887127
SID: 93367925
Canonical SMILES
CCCCCCC(=O)N[C@@H]1CNC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC1=O
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Compound Formula C35H56N6O6
Compound Structure
Protein Name
Dihydrofolate reductase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P00374
Gene Name
DHFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000341 WIL2 Homo sapiens (Human)  1
1
IC50 = 250 nM
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