Brief Information of the Compound and Protein
Compound Name
(E)-6-{2-[2-tert-Butyl-4-(4-fluoro-phenyl)-6-phenyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one
    Show/Hide
PubChem ID
CID: 5281970
SID: 14807595
Canonical SMILES
CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1
    Show/Hide
Compound Formula C27H26FNO3
Compound Structure
Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P04035
Gene Name
HMGCR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS