Brief Information of the Compound and Protein
Compound Name
(E)-6-{2-[4-(4-Fluoro-phenyl)-2,6-diisopropyl-pyrimidin-5-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one
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PubChem ID
CID: 73348335
Canonical SMILES
CC(C)c1nc(C(C)C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(n1)-c1ccc(F)cc1
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Compound Formula C23H27FN2O3
Compound Structure
Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P04035
Gene Name
HMGCR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 4.8 nM
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