Brief Information of the Compound and Protein
Compound Name
2-(4-{[(2,4-Diamino-quinazolin-6-yl)-prop-2-ynyl-amino]-methyl}-benzoylamino)-pentanedioic acid
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PubChem ID
CID: 13989362
Canonical SMILES
C#CCN(Cc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)c1ccc2nc(N)nc(N)c2c1
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Compound Formula C24H24N6O5
Compound Structure
Protein Name
Dihydrofolate reductase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P00374
Gene Name
DHFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000341 WIL2 Homo sapiens (Human)  1
1
IC50 = 5.3 nM
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