Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-((2-amino-4-hydroxyquinazolin-6-yl)methoxy)benzamido)pentanedioic acid
    Show/Hide
 PubChem ID
CID: 135471854
SID: 26688787
Canonical SMILES
Nc1nc(O)c2cc(COc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)ccc2n1
    Show/Hide
Compound Formula C21H20N4O7
Compound Structure
Protein Name
 Protein Info 
Dihydrofolate reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P00374
Gene Name
DHFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000341 WIL2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 170 nM