Brief Information of the Compound and Protein
Compound Name
5-(2-Bromo-acetylamino)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanoic acid
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PubChem ID
CID: 13844635
Canonical SMILES
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)NC(CCCNC(=O)CBr)C(O)=O
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Compound Formula C22H26BrN9O4
Compound Structure
Protein Name
Dihydrofolate reductase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P00375
Gene Name
DHFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000343 L1210/R81 Mus musculus (Mouse)  1
1
IC50 = 46 nM
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